The number of days without sync until the connection is considered unresponsive is configurable in the Microsoft Intune admin center. Once the connection is established, the services are expected to sync with each other at least once every 24 hours. This opens the Microsoft 365 Defender portal at, which replaces the use of the previous portal at. Select Endpoint security > Microsoft Defender for Endpoint, and then select Open the Microsoft Defender Security Center. Sign in to the Microsoft Intune admin center. To enable Microsoft Defender for Endpoint You only need to enable Microsoft Defender for Endpoint a single time per tenant. Set up requires administrative access to both the Microsoft Defender Security Center, and to Intune. The first step you take is to set up the service-to-service connection between Intune and Microsoft Defender for Endpoint. Enable Microsoft Defender for Endpoint in Intune For more information, see MDE Security Configuration Management. This scenario is called Security Management for Microsoft Defender for Endpoint and requires configuring the Allow Microsoft Defender for Endpoint to enforce Endpoint Security Configurations toggle to On. In addition to managing settings for Microsoft Defender for Endpoint on devices you manage with Intune, you can manage Defender for Endpoint security configurations on devices that aren’t enrolled with Intune. App protection polices work with both enrolled and unenrolled devices.īefore you start, your environment must meet the prerequisites to use Microsoft Defender for Endpoint with Intune.
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